Buy Omeprazole 20mg No. 30 online.
Brand: Chemical-Pharmaceutical Plant AKRIKHIN, JSC
Drug form: Capsules
Manufacturers: Russia
Active substance: Omeprazole
Group: Inhibitor of H + -K + -ATPase. Antiulcer drug
Expiration date: 2 years
Omeprazole 20mg No. 30
Indications for use of Omeprazole are:
Peptic ulcer of the stomach and duodenum in the acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive and ulcerative lesions of the stomach and duodenum associated with the intake of NSAIDs.
Pharmachologic effect: H + -K + -ATPase inhibitor. Inhibits the activity of H + -K + -ATPase in parietal cells of the stomach and thereby blocks the final stage of the secretion of hydrochloric acid. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus. Due to a decrease in acid secretion, it reduces or normalizes the effect of acid on the esophagus in patients with reflux esophagitis. Omeprazole has a bactericidal effect on Helicobacter pylori. The eradication of H. pylori with the simultaneous use of omeprazole and antibiotics allows you to quickly stop the symptoms of the disease, achieve a high degree of healing of the damaged mucosa and persistent long-term remission, and reduce the likelihood of bleeding from the gastrointestinal tract.
Pharmacokinetics:
When taken orally, it is rapidly absorbed from the gastrointestinal tract. Penetrates into the parietal cells of the gastric mucosa. Plasma protein binding is about 95%, mainly albumin. Biotransformed in the liver. It is excreted by the kidneys - 72-80%, with feces - about 20%. T1 / 2 0.5-1 hours. In patients with chronic liver diseases, T1 / 2 increases to 3 hours.